Quiniron Injection® 500mg

Quiniron Injection® 500mg

Quiniron Injection® 500mg

Category:

Antimalarial Injection

Product Overview:

Injectable antimalarial for severe and complicated malaria, especially chloroquine-resistant P. falciparum cases requiring slow IM/IV administration.

Composition:

Each 2 ml contains:
Quinine Dihydrochloride BP – 500 mg,
Water for Injection BP – q.s.

Colour: Clear Colourless Solution

Details

Indication
Dosage & Administration
Pack Size
Route of Administration
Shelf life
Storage Instruction
Precautions
Side Effects

  • For treatment of severe/complicated malaria and P. falciparum resistant to chloroquine, via slow IM/IV administration.

  • Each 2 ml ampoule contains Quinine Dihydrochloride BP 500 mg with Water for Injection BP q.s. Adults: 10 mg/kg (max 700 mg) diluted in 10 ml/kg 5% dextrose infused over 4 hrs, repeated every 8 hrs; as directed by physician.

  • Primary Packaging

    2 ml Ampoule

  • Secondary Packaging

    One Inner Tray of 10 Ampoules per Carton with Insert

  • Shrink Pack

    10 Carton Shrinked Wrapped.

  • Tertiary Packaging

    7-Ply Export Shipper

  • Slow Intramuscular (IM) / Intravenous (IV) injection only

  • 36 Months

  • Store in a cool, dry and dark place at a temperature not exceeding 30°C.

  • Confirm quinine concentration before infusion. Monitor pulse and BP during infusion, especially in elderly, pregnant patients and those with cardiovascular disease. Monitor blood glucose as quinine can cause hypoglycemia. Use cautiously in renal/hepatic impairment.

  • Cinchonism (headache, tinnitus, nausea, vomiting, abdominal pain, blurred vision), rare hypersensitivity reactions (rash, pruritus, angioedema), and in toxic doses hearing loss, visual disturbances, arrhythmia, hypotension.

Reason of use

Effective treatment for severe and complicated malaria (P. falciparum).
Used when chloroquine-resistant malaria is suspected and alternative antimalarials cannot be given.
Suitable for slow IM/IV administration in critical malaria cases.

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